클로나제팜 사용의 현실적 문제들

• 영문명: Practical Issues With Clonazepam Use
• 발행기관: 대한신경정신의학회
• 저자명: 강웅구 김세현 최영숙 이규영 김용식 정인원
• 간행물 정보: 『신경정신의학』제62권 제1호, 21~45쪽, 전체 25쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2023.02.28

영문 초록

Clonazepam, a 7-nitrobenzodiazepine, has been used for the treatment of various neuropsychiatric disorders such as seizures, sleep disorders, panic disorders, anxiety, and movement disorders. However, clonazepam is officially approved as a therapeutic drug only for epilepsy and panic disorders in Korea. This raises ethical issues in clinical practice, as clonazepam is prescribed off-label for most neuropsychiatric disorders in many other countries as well. The misuse and abuse of clonazepam as a recreational drug have also been commonly reported in global literature. In this review, as a therapeutic drug as the authors aim to highlight the pharmacological aspects, clinical effects, and potential addictive risks of clonazepam use, by reviewing the current literature on clonazepam to increase its clinical use by accurately understanding and identifying its psychopharmacological benefits and characteristics. However, establishing the risk/benefit ratio of clonazepam for use in specific clinical situations is difficult because of the lack of adequate updated data. Therefore, the use of clonazepam needs to be approached from the point of view of personalized drug treatment rather than following fixed guidelines which would not reflect the current real-world clinical practices.

목차

서론

클로나제팜의 특성

클로나제팜 사용시 고려해야 하는 문제들

임상적 사용

특수 집단에서의 사용

클로나제팜의 부작용

클로나제팜의 감량 및 중단

결론

REFERENCES

키워드

Psychiatric disorders Benzodiazepine Clonazepam