양극성 장애에서의 수면장애: 일주기 리듬의 교란과 수면 무호흡증을 중심으로

• 영문명: Sleep Disorders in Bipolar Disorders: A Narrative Review on Circadian Rhythm Disturbances and Sleep Apnoea
• 발행기관: 대한수면의학회
• 저자명: 이준희 오상훈
• 간행물 정보: 『수면정신생리』재29권 제2호, 40~44쪽, 전체 5쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2022.12.31

영문 초록

Bipolar disorders are a group of mood disorders characterised by relapsing mood episodes throughout the course of illness. Patients with bipolar disorders commonly present with various sleep problems. Patients in a manic episode generally show decreased need of sleep and those in a depressed episode frequently complain about hypersomnia. Current literature even points to evidence that patients with bipolar disorder in euthymic state may still show signs of sleep disturbances when compared to the general population. Clinicians may also note intricate interactions between changes of circadian rhythm and evolution of mood episodes in patients with bipolar disorder. Also, commonly prescribed medications which plays a crucial role in treatment of bipolar disorders including mood stabilisers and antipsychotic medications often cause significant weight gain over time. Being a risk factor of sleep apnoea, weight gain can predispose the patient to develop sleep apnoea. In this narrative review, we summarised current evidence and literature regarding characteristics of circadian rhythm and comorbid sleep apnoea in patients with bipolar disorder. We also present literature regarding implications of circadian disturbance and comorbid sleep apnoea in managing patients with bipolar disorder.

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키워드

Bipolar disorder Circadian rhythm disturbance Sleep apnoea Sleep disorder