비만성 저환기 증후군의 조기 진단 및 치료 전략

• 영문명: Early Diagnosis and Treatment Strategies of Obesity Hypoventilation Syndrome
• 발행기관: 대한수면의학회
• 저자명: 김환희(Hwan Hee Kim) 이상학(Sang Haak Lee) 김세원(Sei Won Kim)
• 간행물 정보: 『수면정신생리』제29권 제1호, 4~8쪽, 전체 5쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2022.06.30

영문 초록

Obesity hypoventilation syndrome (OHS) is defined as the triad of obesity (body mass index, [BMI] ≥ 30 kg/m2), daytime hypercapnia (PaCO2 ≥ 45 mm Hg), and sleep breathing disorder, after excluding other causes for hypoventilation. As the obese population increases worldwide, the prevalence of OHS is also on the rise. Patients with OHS have poor quality of life, high risk of frequent hospitalization and increased cardiopulmonary mortality. However, most patients with OHS remain undiagnosed and untreated. The diagnosis typically occurs during the 5th and 6th decades of life and frequently first diagnosed in emergency rooms as a result of acute-on-chronic hypercapnic respiratory failure. Due to the high mortality rate in patients with OHS who do not receive treatment or have developed respiratory failure, early recognition and effective treatment is essential for improving outcomes. Positive airway pressure (PAP) therapy including continuous PAP (CPAP) or noninvasive ventilation (NIV) is the primary management option for OHS. Changes in lifestyle, rehabilitation program, weight loss and bariatric surgery should be also considered.

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고이산화탄소혈증 비만성저환기증후군 비침습적기계환기 수면호흡장애 저환기 Hypercapnia Hypoventilation Noninvasive ventilation Obesity hypoventilation syndrome Sleep breathing disorder