수면과 알츠하이머 치매의 관계

• 영문명: Relationship Between Sleep and Alzheimer’s Dementia
• 발행기관: 대한수면의학회
• 저자명: 이경환(Kyoung Hwan Lee) 김호찬(Ho Chan Kim)
• 간행물 정보: 『수면정신생리』제29권 제1호, 1~3쪽, 전체 3쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2022.06.30

영문 초록

Sleep is associated with Alzheimer’s dementia. Many previous researches have shown that inadequate sleep is one of the risk factors that predict Alzheimer’s dementia. The causal mechanism of this association is not clear. Slow wave sleep and REM sleep are critical stages in memory consolidation, and by sequential hypothesis both stages are important. Deposition of amyloid beta and tau, the main pathology of Alzheimer’s dementia, are also associated with sleep. This review provides the association of sleep and Alzheimer’s dementia, and future research is necessary to examine the specific mechanism of this association between sleep and Alzheimer’s dementia, which may lead to an early intervention in sleep.

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키워드

수면 아밀로이드 베타 알츠하이머 치매 타우 Alzheimer Amyloid beta Dementia Sleep Tau