Overview of the status of the development of antiviral drugs for COVID-19

• 영문명: Overview of the status of the development of antiviral drugs for COVID-19
• 발행기관: 한국축산식품학회
• 저자명: Seung Yun Lee Ji Hyeop Kang Hea Jin Kang Sun Jin Hur
• 간행물 정보: 『Food and Life』제2020권 제2호, 55~69쪽, 전체 15쪽
• 주제분류: 농수해양 > 식품과학
• 파일형태: PDF
• 발행일자: 2020.07.31

영문 초록

In this study, we surveyed worldwide media reports and research papers on the development of vaccines and antiviral drugs for COVID-19 treatment published over the past few months. We found that more studies were being conducted on the use of already approved drugs (remdesivir, lopinavir/ritonavir, chloroquine, niclosamide, and ivermectin) as new COVID-19 treatments, than on the development of new antiviral drugs. This could be due to the urgent need for drug development. We found that till date, there seem to be no results on current or future COVID-19 vaccine development. However, media reports showed that numerous companies have invested in vaccine development and some clinical trials are already underway (mostly in phase I–II). According to the results of our survey, the drugs that have been previously approved to treat other diseases have not yet been found to be very effective in treating COVID-19 patients; however, remdesivir is the most promising drug. Due to the pandemic situation, the number of patients participating in these clinical trials, compared to that in other previous clinical studies, is small. Therefore, due to the low reliability of the findings, additional experiments must be continued.

목차

Introduction

Status of the vaccine development

Status of antiviral drug development

Conclusion

Conflicts of Interest

Acknowledgments

Ethics Approval

Author Contributions

Author Information

References

키워드

SARS-CoV-2 COVID-19 vaccine development antiviral drug