Effects of sleep deprivation on coronary heart disease

• 영문명: Effects of sleep deprivation on coronary heart disease
• 발행기관: 대한생리학회-대한약리학회
• 저자명: Ran Wei Xiaoye Duan Lixin Guo
• 간행물 정보: 『The Korean Journal of Physiology & Pharmacology』제26권 제5호, 297~305쪽, 전체 9쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2022.09.30

영문 초록

The presence of artificial light enables humans to be active 24 h a day. Many people across the globe live in a social culture that encourages staying up late to meet the demands of various activities, such as work and school. Sleep deprivation (SD) is a severe health problem in modern society. Meanwhile, as with cardiometabolic disease, there was an obvious tendency that coronary heart disease (CHD) to become a global epidemic chronic disease. Specifically, SD can significantly increase the morbidity and mortality of CHD. However, the underlying mechanisms responsible for the effects of SD on CHD are multilayered and complex. Inflammatory response, lipid metabolism, oxidative stress, and endothelial function all contribute to cardiovascular lesions. In this review, the effects of SD on CHD development are summarized, and SD-related pathogenesis of coronary artery lesions is discussed. In general, early assessment of SD played a vital role in preventing the harmful consequences of CHD.

목차

INTRODUCTION

SD INCREASES THE RISK OF CHD

MECHANISMS OF CHD CAUSED BY SD

SUMMARY

FUNDING

ACKNOWLEDGEMENTS

CONFLICTS OF INTEREST

REFERENCES

키워드

Coronary heart disease Inflammatory response Lipid metabolism Oxidative stress Sleep deprivation