기계적 혈전제거술을 시행한 허혈성 뇌졸중 환자의 뇌재관류 손상 위험요인과 임상결과

• 영문명: Risk Factors and Clinical Outcomes of Brain Reperfusion Injury after Mechanical Thrombectomy for Ischemic Stroke
• 발행기관: 한국기초간호학회
• 저자명: 문지현(Moon, Ji Hyun) 최혜란(Choi, Hye-Ran)
• 간행물 정보: 『Journal of Korean Biological Nursing Science』제23권 제3호, 217~226쪽, 전체 10쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2021.08.31

영문 초록

Purpose: The aim of this study was to investigate the risk factors for brain reperfusion injury in ischemic stroke patients and to analyze the clinical outcomes. Methods: A retrospective study was conducted in 168 patients who underwent mechanical thrombectomy. The data were analyzed using descriptive statistics, t-test, Mann-Whitney U test, Chi-Square test, Fisher’s exact test, and logistic regression with IBM SPSS/WIN 24.0. Results: Brain reperfusion injury occurred in 67 patients (39.9%) with a low favored outcome (χ2= 6.01, p= .014). On multivariable analysis, blood urea nitrogen (Odds ratio [OR]= 1.14, 95% Confidence interval [CI]= 1.06-1.23), aphasia (OR= 6.16, CI= 1.62-23.40), anosognosia (OR= 4.84, CI= 1.13-20.79), presence of both aphasia and anosognosia (OR= 7.33, CI = 1.20-44.60), and time required to achieve targeted blood pressure (OR = 1.00, CI = 1.00-1.00) were identified as risk factors for brain reperfusion injury. A statistically significant difference was detected in clinical outcomes, including hemorrhagic transformation (χ2= 6.32, p= .012), intensive care unit length of stay (Z= -2.08, p= .038), National Institute of Health Stroke scale score at discharge (Z= -3.14, p= .002), and modified Rankin Scale score at discharge (Z= -2.93, p= .003). Conclusion: This study identified the risk factors and presented the clinical outcomes of brain reperfusion injury. It is necessary to consider these risk factors for evaluating the patients and to establish nursing interventions and strategies.

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허혈성 뇌졸중 혈전제거술 뇌재관류 손상 Ischemic stroke Thrombectomy Brain Reperfusion injury