8주간의 유산소 운동강도에 따른 어린 생쥐의 체중, 식이효율, 뇌의 비만조절 인자(AMPK), 활성산소(MDA), 항산화효소(SOD)의 차이

• 영문명: Differences in Body Weight, Dietary Efficiency, Brain Obesity Control Factor (AMPK), Reactive Oxygen Species (MDA), and Antioxidant Enzymes (SOD) in Young Mice According to the Intensity of Aerobic Exercise for 8 Weeks
• 발행기관: 한국기초간호학회
• 저자명: 전미양(Jeon, Mi Yang)
• 간행물 정보: 『Journal of Korean Biological Nursing Science』제23권 제3호, 247~255쪽, 전체 9쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2021.08.31

영문 초록

Purpose: The goal of this study was to see how different aerobic exercise intensities affected AMP-activated protein kinase (AMPK), reactive oxygen, and antioxidant enzymes in young mice during an 8-week period. Methods: Forty male C57BL/6 mice, aged seven weeks, were randomly assigned to one of four groups: control (n= 10), low-intensity exercise (n= 10), moderate-intensity exercise (n= 10), and high-intensity exercise (n= 10). For eight weeks, aerobic activity was performed once a day for 35–40 minutes, five days a week. The data were analyzed using descriptive statistics, analysis of variance (ANOVA), chi-squared tests, and the Tukey test in the SPSS/WIN 25.0 program. Results: Weight (p= .001) was substantially different between the moderate-intensity exercise group and the control group in AMPK (p< .001). In addition, there were no significant differences between the moderate-intensity exercise group and the control group in reactive oxygen malondialdehyde (MDA) levels (p= .136) and antioxidant enzyme superoxide dismutase (SOD) levels (p= .521). Conclusion: These findings suggest that moderate-intensity aerobic exercise increased AMPK activation and helped young mice shed weight.

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생쥐 운동 항산화효소 활성산소, 5’아데노신 1인산염 활성화 단백질 인산화효소 Antioxidants AMP-activated protein kinases Reactive oxygen species Exercise Mice