학술논문
Bioconversion Products of Whey by Lactic Acid Bacteria Exert Anti-Adipogenic Effect
이용수 17
- 영문명
- 발행기관
- 한국축산식품학회
- 저자명
- Ji Soo Lee In Kyung Hyun Ji-Won Yoon Hye-Jin Seo Seok-Seong Kang
- 간행물 정보
- 『Food Science of Animal Resources』Food Science of Animal Resources 제41권 제1호, 145~152쪽, 전체 8쪽
- 주제분류
- 농수해양 > 식품과학
- 파일형태
- 발행일자
- 2021.01.31
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국문 초록
영문 초록
Microbial bioconversion using lactic acid bacteria (LAB) provides several human health benefits. Although whey and whey-derived bioactive compounds can contribute to an improvement in human health, the potential anti-obesity effect of whey bioconversion by LAB has not been well studied. This study aimed to investigate whether bioconversion of whey by Pediococcus pentosaceus KI31 and Lactobacillus sakei KI36 (KI31-W and KI36-W, respectively) inhibits 3T3-L1 preadipocyte differentiation. Both KI31-W and KI36-W reduced intracellular lipid accumulation significantly, without decreasing 3T3-L1 preadipocyte proliferation. In addition, obesity-related transcription factor (peroxisome proliferator-activated receptor γ) and genes (adipocyte fatty acidbinding protein and lipoprotein lipase) were down-regulated significantly in 3T3-L1 cells in the presence of KI31-W and KI36-W. Collectively, these results suggest that bioconversion of whey by LAB exhibits anti-adipogenic activity and may be applied as a therapeutic agent for obesity.
목차
Introduction
Materials and Methods
Results and Discussion
Conflicts of Interest
Acknowledgements
Author Contributions
Ethics Approval
References
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