남성 근로자의 비만이 adiponectin과 leptin의 생리적 농도와 대사증후군 진단지표에 미치는 영향

• 영문명: Effects of Obesity on the Physiological Levels of Adiponectin, Leptin and Diagnostic Indices of Metabolic Syndrome in Male Workers
• 발행기관: 한국직업건강간호학회
• 저자명: 허경화(Heo, Kyung Hwa) 원용림(Won, Yong Lim) 고경선(Ko, Kyung Sun) 김기웅(Kim, Ki Woong)
• 간행물 정보: 『한국직업건강간호학회지』제18권 제1호, 44~54쪽, 전체 11쪽
• 주제분류: 의약학 > 간호학
• 파일형태: PDF
• 발행일자: 2009.05.31

영문 초록

The aim of this study was to examine the effects of obesity on the physiological levels of adiponectin, leptin and components of metabolic syndrome (MS) in male workers, aged 30-40 years. Methods: Body mass index (BMI) was measured with Anthropometric equipment. Blood pressure and serum parameters were measured with an automatic digital sphygmomanometer and autochemical analyzer, respectively. Adiponectin and leptin were analysed by ELISA kits and MS was defined based on the NCEP-ATP III. Results: Body fat mass of waist and hip, systolic and diastolic blood pressure were significantly higher, as expected, in the BMI＞ 25㎏/㎡ in comparison with the BMI≤25㎏/㎡. While fasting glucose, insulin, HOMA-IR and leptin in the BMI＞25㎏/㎡ were also significantly higher compared with BMI≤25㎏/㎡, HDL- cholesterol and adiponectin were significantly higher in BMI≤25㎏/㎡. On multiple logistic regression analysis for the components of MS, exercise, adiponectin and leptin were an only independent factor for MS in non-obese male workers(BMI≤25㎏/㎡) after adjustment for age, cigarette smoking and drinking habits. Conclusion: These results suggested that the obesity in men was associated with physiological levels of adiponectin and leptin contributing to feedback control of MS and that dysfunction and/or declination in feedback control system associated with changes in physiological levels of neurptrophics: adiponectin and leptin might ultimately induce MS.

목차

Ⅰ. 서 론

Ⅱ. 연구 방법

Ⅲ. 연구 결과

Ⅳ. 논 의

Ⅴ. 결 론

키워드

비만 대사증후군 진단지표 Adiponectin Leptin 남성 근로자 Metabolic syndrome Adiponectin Leptin Male workers