소아청소년에서 발생한 대상포진의 임상적 특징

• 영문명: Clinical characteristics of herpes zoster in children and adolescents
• 발행기관: 조선대학교 의학연구원
• 저자명: 김가희(Ga Hee Kim) 이재희(Jae Hee Lee) 문경래(Kyung Rye Moon)
• 간행물 정보: 『The Medical Journal of Chosun University』제44권 제1호, 33~37쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2019.04.30

영문 초록

Purpose: The incidence of pediatric herpes zoster has been increasing year by year. Pediatric herpes zoster is generally known to be less severe than adult cases, but may cause various complications such as secondary bacterial infections, encephalitis, meningitis, and Ramsay Hunt syndrome. In this study, we performed epidemiological and clinical investigations of children and adolescents diagnosed as herpes zoster. The incidence and clinical factors associated with complications of herpes zoster were studied. Methods: This study was retrospectively analyzed the medical records of 62 patients under 18 years who were diagnosed and treated with herpes zoster at Chosun University Hospital from 2007 to 2017. This patients were evaluated with regard to gender, age, dermatomal distributions, accompanying symptoms, underlying disease, treatment and complications. These patients were divided into two groups according to the presence or absence of complications. Results: Children under 18 years old account for 3.2% of all herpes zoster patients who were hospitalized at Chosun University Hospital from 2007 to 2017. The incidence of males was higher than that of females. The number of enrolled patients was increasing according to age. The number and the proportion of pediatric patients has been increasing year by year. Lesions of herpes zoster were most frequently found in the thoracic region, followed by the cervical, trigeminal, lumbar regions. The most common accompanying symptom was pain, followed by pruritus, fever, headache. Among the 62 cases, 27 cases (27.4%) were complicated by herpes zoster. Ramsay Hunt syndrome was the most common (16.1%), followed by meningitis and herpes ophthalmicus. Neither secondary bacterial infection nor postherpetic neuralgia were observed. Skin lesions in the trigeminal dermatomes was associated with complications (p=0.006). The mean of hospitalization period is longer in the group with complications (p=0.003). The patients accompanying symptoms such as headache was more likely to occur complications (p value＜0.05). There was no difference in age, sex, and underlying disease between the two groups. Conclusion: Patients with complications had longer duration of treatment and had more frequent with trigeminal and cervical region. The patients accompanying symptom such as headache were more likely to occur complications.

목차

서론

대상 및 방법

결과

고찰

키워드

Herpes zoster Child Adolescents Complications