중첩증후군：만성 폐쇄성 폐질환을 가 진 폐쇄성 수면무호흡-저호흡 증후군

• 영문명: Overlap Syndrome：Obstructive Sleep Apnea-Hypopnea Syndrome in Patients with Chronic Obstructive Pulmonary Disease
• 발행기관: 대한수면의학회
• 저자명: 최영미(Youngmi Choi)
• 간행물 정보: 『수면정신생리』제15권 제2호, 67~70쪽, 전체 4쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2008.12.31

영문 초록

Overlap syndrome can be defined as a coexistence of chronic obstructive pulmonary disease (COPD) and sleep apnea-hypopnea syndrome (SAHS). The association of COPD and SAHS has been suspected because of the frequency of both diseases. Prevalence of COPD and SAHS is respectively 10 and 5% of the adult population over 40 years of age. However, a recent study has shown that the prevalence of SAHS is not higher in COPD than in the general population. The coexistence of the two diseases is only due to chance. SAHS does not affect the pathophysiology of COPD and vice versa. Prevalence of overlap syndrome is expected to occur in about 0.5% of the adult population over 40 years of age. Patients with overlap syndrome have a more profound hypoxemia, hypercapnia, and pulmonary hypertension when compared with patients with SAHS alone or usual COPD patients without SAHS. To treat the overlap syndrome, nocturnal noninvasive ventilation (NIV) or nasal continuous positive airway pressure (nCPAP) can be applied with or without nocturnal oxygen supplement.

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키워드

만성폐쇄성폐질환 수면 무호흡-저호흡 증후군 중첩증후군 Chronic obstructive pulmonary disease (COPD) Sleep apnea-hypopnea syndrome (SAHS) Overlap syndrome