기면증：임상 양상진단 그리고 치료

• 영문명: Narcolepsy：Clinical Feature, Diagnosis and Treatment
• 발행기관: 대한수면의학회
• 저자명: 신홍범(Hong Beom Shin)
• 간행물 정보: 『수면정신생리』제17권 제2호, 63~68쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2010.12.31

영문 초록

Narcolepsy is a central neurologic system disease. It begins early in life with disabling symptoms including excessive daytime sleepiness, cataplexy, sleep paralysis, hypnagogic hallucination and nocturnal sleep fragmentation. Patient with typical symptoms of narcolepsy is diagnosed by objective data from nocturnal polysomnography and multiple sleep latency tests. Narcolepsy is controlled with various medications. Nowadays, modafinil with favorable side effects profiles compared with traditional stimulant is mainly used. Gamma hydroxyl butyrate is effective in cataplexy. Cataplexy is also controlled with antidepressant such as Venlafaxine, SSRI, and TCA. As the knowledge of pathophysiology of narcolepsy expands, new treatment including immunological method, application of hypocretin and histamine systems have been tried.

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키워드

기면증 과다수면증 탈력발작 Narcolepsy Hypersomnia Cataplexy