진정제 및 수면제 유발 사건수면

• 영문명: Sedative Hypnotics Induced Parasomnias
• 발행기관: 대한수면의학회
• 저자명: 이유진(Yu Jin Lee)
• 간행물 정보: 『수면정신생리』제19권 제1호, 18~21쪽, 전체 4쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2012.06.30

영문 초록

Parasomnias induced by hypnosedatives are rare but serious side effect. Such parasomnias have not been reported with all hypnosedatives. However, frequent use of hypnosedatives, particularly nonbenzodiazepine receptor agonists is associated with parasomnias. Associated symptoms are sleep eating, sleepwalking with object manipulation, sleep conversations, sleep driving, sleep sex and sleep shopping etc. Mechanisms include high affinity for GABAA receptor, interruption of the consolidation phase of memory formation by drug, pharmacokinetic or pharmacodynamic drug-drug interaction and concomitant administration with alcohol. Managements for parasomnias induced by hypnosedatives involve stopping medication, switch to other medications or nonpharmacological treatment, lowest effective dose of NBRAs (Non-Benzodiazepine Receptor Agonists), taking into consideration drug-drug interactions, identification and treatment of underlying disease states.

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키워드

진정제 수면제 사건수면 유발기전 치료 Hypnosedatives Parasomnia Mechanism Management