폐쇄성 수면 무호흡증과 간질성 폐질환

• 영문명: Obstructive Sleep Apnea in Interstitial Lung Disease
• 발행기관: 대한수면의학회
• 저자명: 김신범(Shin Bum Kim) 이상학(Sang Haak Lee) 강현희(Hyeon Hui Kang)
• 간행물 정보: 『수면정신생리』제24권 제1호, 19~23쪽, 전체 5쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2017.06.30

영문 초록

Obstructive sleep apnea is a common disorder in which respiratory flow decreases or disappears despite respiratory effort due to occlusion of the upper respiratory tract during sleep. Oxidative stress and systemic inflammatory reaction induced by the obstruction cause complications such as hypertension, coronary artery disease, and diabetes and increase cancer incidence. Furthermore, in patients with interstitial lung disease, obstructive sleep apnea has a very high prevalence and is thought to have a close pathophysiological and clinical correlation. In other words, obstructive sleep apnea could be the cause or a complication of interstitial lung disease ; when these two afflictions coexist, the prognosis of the patient is worse. In patients with interstitial lung disease with obstructive sleep apnea, CPAP treatment significantly improved sleep and quality of life, as well as improved morbidity and mortality in a recent study. Therefore, early diagnosis and treatment of obstructive sleep apnea in patients with interstitial lung disease are very important, and additional studies designed to include patients with idiopathic pulmonary fibrosis as well as patients with advanced interstitial lung disease should be performed.

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키워드

간질성 폐질환 수면장애 지속형 양압기 치료 폐쇄성 수면 무호흡증 Obstructive sleep apnea Interstitial lung disease Sleep disorder CPAP treatment