Mixed Adenoneuroendocrine Carcinoma of the Gallbladder

• 영문명: Mixed Adenoneuroendocrine Carcinoma of the Gallbladder
• 발행기관: 조선대학교 의학연구원
• 저자명: Nam-kyu Choi In-ju Cho Ran Hong
• 간행물 정보: 『The Medical Journal of Chosun University』제42권 제1호, 16~20쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2017.03.31

영문 초록

Mixed adenoneuroendocrine carcinoma (MANEC) of the biliary tract is rare. Here, the authors report a case of MANEC of the gallbladder, in which neuroendocrine carcinoma (NEC) exhibited collision and sharp separation from a moderately differentiated adenocarcinoma; these two tumor components made up of more than 30% of the entire tumor, respectively. The tumor metastasized to liver and one lymph node, and the hepatic metastatic component was from an neuroendocrine tumor (NET), while the lymphovascular invasion and lymph node metastasis was attributed to adenocarcinoma. Ki-67 im-munostaining (>50%) and numerous mitotic counts showed the NET exhibited high proliferative activity. Because the neuroendocrine component in biliary MANEC defines prognosis, its identification is of considerable importance.

목차

Introduction

Case report

Discussion

키워드

Adenocarcinoma Neuroendocrine carcinoma Gallbladder