신생아 정맥영양에서 사용되는 두 지방유제 (SMOFlipid？？, ClinOleic？？)의 비교

• 영문명: Comparison of 2 Lipid Emulsions (SMOFlipid^？？, ClinOleic^？？) in Parenteral Nutrition of Newborns
• 발행기관: 조선대학교 의학연구원
• 저자명: 박미선(Mi Seon Park) 최민선(Min Seon Choi) 박상기(Sang Kee Park)
• 간행물 정보: 『The Medical Journal of Chosun University』제41권 제4호, 104~110쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2016.12.31

영문 초록

This study is to make a comparison between the one liquid emulsion with and without fish oil containing higher omega-3 fatty acid in parenteral nutrition (PN) of newborns. Serum chemistry and clinical complications from Medical Records of 76 newborns who had received PN with either SMOFlipid^？？ or ClinOleic^？？ for at least 7 days in NICU at Chosun Univeristy Hospital from January 2011 to December 2014 were reviewed retrospectively. Serum chemistry revealed no significant difference between the two groups except for total bilirubin (TB), glucose, blood urea nitrate (BUN), creatine (Cr), and cholesterol, but they even were not clinically significant as their values were within almost normal range. In terms of the difference in clinical complications, the incidence of cholestasis was higher in newborns given ClinOleic^？？. However, there was no statistically significance. In this study, no significant difference between ClinOleic^？？ and SMOFlipid^？？ in their clinical efficacy was proven. But, considering the advantage of omega-3 fatty acid in reduction of cholestasis and infection risk, more studies may be needed using lipid emulsions containing higher content of fish oil with high omega-3 fatty acid, and they may be better if done with larger groups.

목차

서론

연구대상 및 방법

결과

고찰

결론

키워드

Fish oil Olive oil Parenteral nutrition Oomega-3 fatty acid Newborn