루푸스 환자에서 발생한 크립토코쿠스 네오포르만스에 의한 뇌수막염

• 영문명: Meningoencephalitis by Cryptococcus neoformans in a Patient with Systemic Lupus Erythematosus
• 발행기관: 조선대학교 의학연구원
• 저자명: 김영숙(Young Sook Kim) 문도식(Do Sik Moon) 김윤성(Yun Sung Kim)
• 간행물 정보: 『The Medical Journal of Chosun University』제41권 제1호, 4~8쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2016.03.31

영문 초록

Invasive fungal infection can be a lethal complication in systemic lupus erythematosus (SLE). Crytococcus neoformans, as one of the most common pathogenic species worldwide, can cause infection disease in human. The central nervous system (CNS) is a common site for cryptococcal infection which usually presents cryptococcal meningitis. The cryptococcal meningitis is a recognized complication of SLE, with high mortality rates, particularly in those treated with immunosuppressive agents. However, it is difficult to differentiate infectious meningitis and neuropsychiatric lupus because of the clinical manifestations are unspecific and frequently are confused with lupus activity. So a early diagnosis and treatment is very important for its significant mortality and morbidity. We report the case of fatal meningoencephalitis by Cryptococcus neoforman in a 44 years old patient with SLE.

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키워드

Cryptococcus neoformans Meningoencephalitis Systemic lupus erythemaosus