소아 마이코플라즈마 폐렴에서 Macrolide 항생제 치료 후 열의 지속과 관련된 예후 인자

• 영문명: Prognostic Factors Related to The Duration of Fever after Macrolides Treatment in Children with Mycoplasma pneumoniae Pneumonia
• 발행기관: 조선대학교 의학연구원
• 저자명: 이재성(Jae sung Lee) 이기강(Ki Kang Lee) 김용욱(Yong Wook Kim) 김경심(Kyoung Sim Kim) 김은영(Eun Young Kim) 김 령(You
• 간행물 정보: 『The Medical Journal of Chosun University』제40권 제3호, 93~100쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2015.09.30

영문 초록

The present study aimed to identify the factors that can clinically predict responses to macrolides treatment in patients with Mycoplasma pneumoniae pneumonia. Of the patients admitted to the pediatrics department of Kwangju Christian Hospital during December 2012 to March 2015, 195 patients who had pneumonia according to findings of chest radiography, positive Mycoplasma IgM, and fever at the time of admission were selected as study subjects. Patients were divided into one group wherein the duration of fever after macrolides treatment was 3 days or less and another group wherein the duration of fever was 4 days or more (169 patients [86.7%] vs 26 patients [13.3%]). In the group with fever duration of 4 days or more, a greater number of patients had a history of atopic dermatitis (3.6% vs 15.4%, p=0.11), and the symptom duration before admission was longer (cough: 4.04 days vs 6.38 days, p<0.001; fever: 3.96 days vs 6.08 days, p<0.001). Moreover, according to laboratory test results in the group with fever duration of 4 days or more, LDH levels were high (648.16 IU/L vs 829.92 IU/L, p=0.001), and there was a significant correlation between LDH levels and the duration of fever after macrolides treatment.

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키워드

Mycoplasma pneumoniae pneumonia Children Atopic dermatitis LDH Steroid