Paraneoplastic Neutrophilia Originating from an Anaplastic Transformation of Papillary Thyroid Carcinoma in a Metastatic Pleural Lesion

• 영문명: Paraneoplastic Neutrophilia Originating from an Anaplastic Transformation of Papillary Thyroid Carcinoma in a Metastatic Pleural Lesion
• 발행기관: 조선대학교 의학연구원
• 저자명: Jeong Su Baek Sung Hyun Lee Ae Ri Cho Joo Young Lee Jeong Mi Jang Seung Suk Lee Hyo Rak Lee
• 간행물 정보: 『The Medical Journal of Chosun University』제39권 제1호, 39~42쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.03.31

영문 초록

Marked neutrophilia associated with neoplasia is a relatively rare finding and has been considered as a paraneoplastic manifestation. Thyroid cancer seldom presents with paraneoplastic leukocytosis. We report on a case of a 69-year-old man who presented with paraneoplastic leukocytosis seven months after undergoing total thyroidectomy and I-131 therapy for treatment of papillary thyroidcarcinoma. We found neither bone marrow involvement of malignant cells nor hematologic malignancy. Based on elevated levels of serum granulocyte colony-stimulating factor, we concluded that the cause was paraneoplastic leukocytosis. Another interesting point was the anaplastic transformation in the pleural metastatic site. It usually occurs in the intrathyroid or regional lymph node.

목차

Introduction

Case report

Discussion

키워드

Paraneoplastic leukocytosis Anaplastic carcinoma Papillary thyroid carcinoma Anaplastic transformation Granulocyte colony-stimulating factor