Mechanical stress가 골조직세포군에 미치는 영향

• 영문명: THE EFFECTS OF MECHANICAL STRESS ON CULTURED BONE CELL POPULATIONS
• 발행기관: 대한치과교정학회
• 저자명: 김상태(Sang-Tae Kim) 차경석(Kyung-Suk Cha)
• 간행물 정보: 『The Korean Journal of Orthodontics』제24권 제1호, 105~114쪽, 전체 10쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1994.03.31

영문 초록

The movement of teeth during orthodontic treatment requires bone remodeling process of bone formation and bone resorption. To find out the changes occuring in the cell itself, mechanical stress was applied to the cell populations involved in the bone metabolism. Bone tissue cell populations were isolated from fetal rat calvaria and divided into OC and OB groups. Following results were obtained from measuring the changes in acid & alkaline phosphatease activity, cyclic AMP and PGE_² production in time lapse after the application of mechanical stress. 1. In case of the marker enzyme of specific bone tissue cell, acid phosphatase activity was high in OC group and alkaline phosphatase activity was high in OB group. 2. After the mechanical stress was applied, acid phosphatase activity was decreased in both OC and OB groups and alkaline phosphatase activity was increase in OB group. 3. When the mechanical stress was applied for 15, 30 and 60 minutes, the production of PGE_² increased in both OC and OB groups, as the time span increased. 4. When the mechanical stress was applied for 20 and 40 minutes, the production of PGE_² increased in both OC and OB groups, as the time span increased.

키워드

Mechanical Stress Bone Cell