오수유(吳茱萸) Evodiae Fructus 방향성물질(芳香性物質)의 약리학적(藥理學的) 연구(硏究)

• 영문명: Pharmacologic-Action of Essential Substance Obtained from Fruits of Evodia rutaecarpa
• 발행기관: 대한약리학회
• 저자명: 노영근(Young Geun Rho) 정지창(Jee Chang Jung) 고계창(Kye Chang Ko) 한대섭(Dae Sup Han)
• 간행물 정보: 『대한약리학잡지』제16권 제1호, 57~63쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1980.06.30

영문 초록

The Pharmacologic action of ethanol extracts and essential substance obtained from fruits of Evodia rutaecarpa are studied. 1) Motility of the isolated rabbit-intestine was decreased in proportion to the concentration of essential substance. 2) Intestinal contraction induced by acetylcholine 10? 6g/ml was inhibited by the essential substance 10^-5g/ml. 3) Contractile responses of the isolated rabbit-intestine by serotonin 10^-5g/ml and histamine 10^-5g/ml were depressed significantly with the essential substance 10^-5g/ml. 4) Alpha adrenergic receptor blocking effect of dihydroergotamine was interfered significantly with the essential substance. 5) Analgesic effect in mice by acetic acid stimulating method was observed significantly with both of the ethanol extracts and essential substance. 6) Blood pressure and respiration of the rabbits were not significantly influenced with the essential substance.