Lactobacillus acidophilus의 장 상피세포에 대한 부착능력 및 장 출혈성 대장균의 부착 억제 능력

• 발행기관: 한국축산식품학회
• 저자명: 김영훈 박순옥 한경식 오세종 유승권 김세헌
• 간행물 정보: 『Food Science of Animal Resources』Korean Journal for Food Science of Animal Resources 제24권 제1호, 86~91쪽, 전체 6쪽
• 주제분류: 농수해양 > 식품과학
• 파일형태: PDF
• 발행일자: 2004.03.31

영문 초록

The ability of probiotics containing Lactobacillus acidophillus to adhere to the intestinal epithelium may play an important role in colonization of the gastrointestinal tract and preventing enteric pathogen such as enterohemorrhagic E. coli(EHEC) O157:H7. In the study, we investigated the adhesion to human intestinal epithelial cells(Ht-29) of strains of L. acidophilus(3 from human, 2 from pig, and 1 from calf). All of the tested strains of L. acidophilus were highly observed adhesion ability(from 10^(6) to 10^(7) cfu/mL), compared to L.rhamunosus GG as contro. Also, adhered strains of L. acidophilus were significatly preserved in serial wash-out steps. However, no correlation could be observed between cell surface hydrophbicity and adhesion abilities of the tested strains of L. acidophilus. Inhibition of adhesion of EHEC O157:H7 was aksi exanubed, a 2 log cycle reduction was observed by all of the tested strains of L. acidophilus. Theses results suggest that the strains of L. acidophilus with high adhesion ability are resistant to wash-out and adhesion abiltiy inhibition by selected strains of L. acidophilus helps to prevent adhesion of EHEC O157:H7 to intestinal epithelial cells.

키워드

adhesion inhibition of EHEC adhesion cell surface hydrophobicity Lactobacillus acidophilus EHEC O157:H7