만성 실혈성 빈혈자 혈장의 적혈구조혈 작용

• 영문명: Erythropoietic Activity in Plasma of Chronic Post-hemorrhagic Anemic Men
• 발행기관: 대한생리학회
• 저자명: 김완태(Kim, Wan-Tai) 정관옥(Chung, Kwan-Ogg) 김윤선(Kim, Yoon-Sun) 조용문(Cho, Yong-Moon) 정원근(Chung, Won-Keun) 남
• 간행물 정보: 『대한생리학회지』제4권 제1호, 55~58쪽, 전체 4쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 1970.06.30

영문 초록

Erythropoietic activity in anemic Plasma of chronic posthemorrhagic anemic men was studied in rats after subcutaneous injection of anemic plasma. Anemic plasma was obtained from blood donors who sold their blood once or twice a week for one or two years to blood bank. Hemoglobin concentrations of 8 blood donors ranged between 4.6 and 8.4 gm/100 ml. Pooled plasma was treated by acidification-boiling method and adjusted to pH 7.5 by adding 0.1 N NaOH. 7ml/kg and 15ml/kg of anemic plasma filtrate was injected to 2 groups of rats respectively for 7 and 8 days. Hemoglobin concentrations, red blood cell counts and reticulocyte counts were observed before and after injection of anemic plasma and no change was induced by the injection. Subsequently, it was concluded that there was no erythropoietin of high titer in the plasma of chronic post-hemorrhagic anemic men.