학술논문
Effect of Methylphenidate on Sleep Parameters in Children with ADHD
이용수 3
- 영문명
- 발행기관
- 대한신경정신의학회
- 저자명
- SangHeon Lee WanSeok Seo HyungMo Sung TaeYoung Choi SoYeun Kim SoJeong Choi BonHoon Koo JongHun Lee
- 간행물 정보
- 『Psychiatry Investigation』제9권 제4호, 384~390쪽, 전체 7쪽
- 주제분류
- 의약학 > 정신과학
- 파일형태
- 발행일자
- 2012.12.31
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국문 초록
영문 초록
Objective-The primary aim of this study was to investigate the acute impact of methylphenidate (MPH) on sleep parameters in attention-deficit/hyperactivity disorder (ADHD) children. The second aim was to investigate the different effects of intermediate- and longacting MPH on sleep parameters. The third aim was to test the different effects of dose and age on sleep parameters.
Methods-Ninety-three ADHD children were enrolled and randomized to two different MPH preparations. Baseline and daily sleep diaries were evaluated for four weeks after taking medication. Weekday and weekend bedtimes, wake-up times, sleep latencies and total sleep times were compared by weeks.
Results-After taking MPH, there was a significant delay in bedtimes and a significant reduction of total sleep time (TST) both on weekdays and at weekends. There was also a significant delay in wake-up time on weekdays. However, the difference was applied to younger age group children only. There was no difference in changes of TST between metadate-CD and OROS-MPH. There also was no difference in changes of TST with different doses of MPH.
Conclusion-MPH had negative impacts on sleep among young ADHD children, but different preparations and doses did not affect the result.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
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