학술논문
Benefical Effects of Sigma-1 Agonist Fluvoxamine for Tardive Dyskinesia and Tardive Akathisia in Patients with Schizophrenia: Report of Three Cases
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- 영문명
- 발행기관
- 대한신경정신의학회
- 저자명
- Yakup Albayrak Kenji Hashimoto
- 간행물 정보
- 『Psychiatry Investigation』제10권 제4호, 417~420쪽, 전체 4쪽
- 주제분류
- 의약학 > 정신과학
- 파일형태
- 발행일자
- 2013.12.31
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국문 초록
영문 초록
Fluvoxamine is a selective serotonin reuptake inhibitor that is approved for psychiatric disorders such as major depressive episodes and obsessive-compulsive disorder. Beside inhibition of serotonin reuptake, fluvoxamine is also a potent agonist of endoplasmic reticulum (ER) protein sigma-1 receptors, which play a role in the pathophysiology of a number of psychiatric and neurodegenerative disorders. This report presents beneficial effects of sigma-1 agonist fluvoxamine on hyperkinetic movement disorders such as tardive dyskinesia and tardive akathisia. Fluvoxamine might be a novel treatmet approach in the treatment of hyperkinetic movement disorders.
목차
INTRODUCTION
CASE
DISCUSSION
REFERENCES
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