주간졸음을 호소하는 노인에서 수면변인과 신경인지기능 세부영역과의 연관성

• 영문명: Relationship of Sleep Parameters with Neurocognitive Function in the Elderly with Excessive Daytime Sleepiness (EDS)
• 발행기관: 대한신경정신의학회
• 저자명: 이정현 김성재 황현국 양정희 이정희
• 간행물 정보: 『신경정신의학』제46권 제6호, 552~559쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2007.11.30

영문 초록

Objectives：Excessive daytime sleepiness (EDS) in the elderly is related to cognitive dysfunction. We aimed to analyze the difference in the neurocognitive function between the elderly groups with and without EDS and examine the correlation between sleep parameters and the neurocognitive function in the elderly with EDS. Methods：Thirty seven subjects who visited Kangwon National University Hospital were recruited. We excluded those who had abnormalities in laboratory examination or chronic systemic diseases. For each subject, a neuropsychological battery in the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD-K) Assessment Packet was applied. Nocturnal polysomnographies were conducted in 16 subjects with EDS. Results：There were no significant differences in the neurocognitive function between EDS positive and EDS negative groups. In the EDS positive group, the amount of stage 1 sleep negatively correlated with scores on Boston naming test, word list memory and Stroop interference, respectively (r=-0.611, -0.583, -0.611). Also, REM sleep amount positively correlated with scores of word list recognition (r=0.568), and limb movement index negatively correlated with scores of word list memory (r=-0.523). Conclusion：The poor sleep quality was associated with impaired language, memory and executive functions. Also, increased limb movements were associated with the memory decline

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키워드

Excessive daytime sleepiness Neurocognitive function Sleep parameter