외적 환경을 고려한 최적의 항우울제 치료

• 영문명: Optimising Antidepressant Use in Clinical Practice：Considering External Factors
• 발행기관: 대한신경정신의학회
• 저자명: 함병주 한창환
• 간행물 정보: 『신경정신의학』제47권 제1호, 22~27쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2008.01.30

영문 초록

Depressive illness is a major public health problem with important medical, social and economic implications. The efficacy of various antidepressants in treating depression has been demonstrated in randomized controlled trials (RCTs). However, these studies do not adequately address the complexities of clinical practice. Although most of RCTs assumed there was no difference in efficacy between the tricyclic antidepressants (TCAs) and serotonin specific reuptake inhibitors (SSRIs), naturalistic studies show that patients who take TCAs often receive subtherapeutic doses for inadequate duration than those with SSRIs. Because the benefits of the implementation of current guidelines are limited, the optimal choice of medication must be guided by detailed history and careful consideration of the real-world efficacy of antidepressants and long-term health care costs.

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Depression Antidepressants Optimal treatment