노인과 노인 제외 성인 주요우울장애 외래 환자 간의 해밀턴 우울증 척도의 우울증상 비교

• 영문명: Comparisons of Depressive Symptoms of the Hamilton Depression Rating Scale between Elderly and Non-Elderly Outpatients with Major Depressive Disorder
• 발행기관: 대한신경정신의학회
• 저자명: 유익기 허정윤 김기원 백지현 유혜진 김동준 전홍진
• 간행물 정보: 『신경정신의학』제54권 제3호, 316~321쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2015.08.21

영문 초록

ObjectivesZZPrevious studies have reported that symptoms of patients with major depressive disorder (MDD) are different according to age groups, and the Hamilton Depression Rating Scale (HDRS) is the most widely used measure to evaluate the symptoms of MDD. However, few previous studies have compared the symptoms of HDRS between the elderly and non-elderly groups. MethodsZZThe study population consisted of 574 subjects with MDD who were ≥18 years old, evaluated using the Mini International Neuropsychiatric Interview and 17 items of HDRS. Differences between two groups were analyzed using independent t-test. A multivariate logistic regression model was used to evaluate associations between age and 17 items from HDRS after controlling for gender, years of education, marital status, and employment status. ResultsZZAmong 574 patients with MDD, there were 80 elderly patients (age≥65) and 494 non-elderly patients (age between 18 and 64). Elderly patients had higher scores on item 5 (middle insomnia) (t=-2.271, p=0.024) and item 6 (late insomnia) (t=-2.280, p=0.023), whereas they had lower scores on item 1 (depressed mood) (t=2.860, p=0.004), item 3 (suicide) (t=2.258, p=0.024), and item 9 (agitation) (t=2.031, p=0.043), although no significant difference in the total HDRS scores was observed between elderly and non-elderly. Multivariate logistic regression showed significant association of elderly with hypochondriasis [adjusted odds ratio (AOR)=1.894, 95% confidence interval (CI) 1.01–3.56] and agitation (AOR=0.50, 95% CI 0.29–0.87). ConclusionZZElderly MDD patients showed more insomnia and hypochondriasis and less depressed mood, suicidal ideation, and agitation than non-elderly.

목차

서 론

방 법

결 과

고 찰

결 론

REFERENCES

키워드

Depression Elderly The Hamilton Depression Rating Scale Outpatients