不眠에 對한 8ᅳChloro-6-Phenyl-4H-s-Triazolo〔4.3ᅳa〕 〔1.4〕 Benzodiazepine 의 効果에 關한 臨床硏究

• 영문명: THE EFFECT OF 8-CHLORO-8-PHENYL-4H-S-TRIAZOLO〔4 -3 -a ]〔1-4〕 BENZODIAZEPIN E ON INSOMNIA : A DOUBLE BLIND CHINICAL STUDY
• 발행기관: 대한신경정신의학회
• 저자명: 李定均 榻秉換
• 간행물 정보: 『신경정신의학』제15권 제4호, 269~278쪽, 전체 10쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1976.10.30

영문 초록

In this studyi authors Examined the hypnotizing effect of Estazolam on patients in I. P. D & 0. P.D. who visited with the chief complaint of insomnia The number of patients selected for this study were 156. They were consisted of 78 neurotics other than depression, 66 depressive patients and 12 mild psychotic patients. Authors applied the double blind clinical method with Estazolam and placebo to the patients. They visited OPD & IPD of Psychiatric department of SNUH (Seoul National University Hospital) from October-1, 1975 to March-31, 1976. The results were as follows: 1. Estazolam had the highest sedating effect to the patients with mild psychosis and the least effect to the neurotics except depression. 2. Total duration of sleep increased approximately 20-30 minutes. 3. No difference was noticed between 2mg and 3mg administrated groups. 4. It seemed that Estazolam had no influencoe on REM sleep pattern (frequency of dream). 5. It was a most effective method to use Estazolam combined with other specific drugs to the patient who had suffered from insemnia for a long period.

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