마우스에서 방풍통성산의 급성 독성 연구

• 영문명: A Study on the Acute Toxicity of Bangpungtongsung-san(Fangfengtongsheng-San) in Mice
• 발행기관: 한방비만학회
• 저자명: 이재훈(Jae Hoon Lee) 심기석(Ki Shuk Shim) 박화용(Hwa Yong Park) 전원경(Won Kyung Jeon) 엄영란(Young Ran Um) 마진열(Jin
• 간행물 정보: 『대한한방비만학회지』제9권 1호, 71~78쪽, 전체 8쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2009.06.30

영문 초록

Objectives Bangpungtongsung-san(Fangfengtongsheng-san) has been traditionally prescribed a a restorative medicine. Methods In this study, we investigated the acute toxicity of water-extracted Bangpungtongsung-san(Fangfengtongsheng-san). 20 male and 20 female mice were orally treated of Bangpungtongsung-san(Fangfengtongsheng-san) at the respective doses of 0 (control group), 1250, 2500 and 5000mg/kg for 14 days. Results We observed survival rates, general toxicity, change of body weight and examined microscopic changes of some organs. Conclusions Compared with the control group, we could not find any toxic alteration in all treated groups (1250, 2500 and 5000mg/kg). LD50 of Bangpungtongsung-san(Fangfengtongsheng-san) might be over 5000mg/kg and it was very safe to ICR mice.

목차

Ⅰ. 서 론

Ⅱ. 재료 및 방법

Ⅲ. 결 과

Ⅳ. 결론 및 고찰

Ⅵ. 참고문헌

키워드

Bangpungtongsung-san Fangfengtongsheng-san Acute toxicity Safety LD50