비만에서 장내 미생물 균총의 역할과 발효 한약의 활용

• 영문명: The Role of Gut Microbiota in Obesity and Utilization of Fermented Herbal Extracts
• 발행기관: 한방비만학회
• 저자명: 박정현(Jung Hyun Park) 김호준(Ho Jun Kim) 이명종(Myeong Jong Lee)
• 간행물 정보: 『대한한방비만학회지』제9권 1호, 1~14쪽, 전체 14쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2009.06.30

영문 초록

Complex microbial communities play an important role in the human health and co-evolved with human in the form of symbiosis. Many literatures provide new evidences that the increased prevalence of obesity cannot be attributed solely to changes in the human genome, nutritional habits, or reduction of physical activity in our daily lives. The intestinal flora was recently proposed as an environmental factor responsible for the control of body weight and energy metabolism. A number of studies suggest that the modulation of gut microbiota affects host metabolism and has an impact on energy storage and demonstrated a role for the gut microbiota in weight gain, fat increase, and insulin resistance. Variations in microbiota composition are found in obese humans and mice and the microbiota from an obese mouse confers an obese phenotype when transferred to an axenic mouse. As well, the gut microbial flora plays a role in converting nutrients into calories. Specific strategies for modifying gut microbiota may be a useful means to treat or prevent obesity. Dietary modulations of gut microbiota with a view to increasing bifidobacteria have demonstrated to reduce endotoxemia and improve metabolic diseases such as obesity. The fermentation of medicinal herbs is intended to exert a favorable influence on digestability, bioavailability and pharmacological activity of herbal extract. Therefore we also expect that the fermented herbal extracts may open up a new area to treat obesity through modulating gut microbiota.

목차

Ⅰ. 서 론

Ⅱ. 고찰 및 결론

Ⅲ. 참고문헌

키워드

Gut Microbiota Obesity Fermented Herbal Extracts