Lethal Catatonia Syndrome 3례

• 영문명: Three Cases of Lethal Catatonia Syndrome
• 발행기관: 대한신경정신의학회
• 저자명: 이인섭 김정기 김종길
• 간행물 정보: 『신경정신의학』제31권 제6호, 1108~1114쪽, 전체 7쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1992.11.30

영문 초록

Lethal catatonia syndrome, first reported by Calmeil and first named by Stauder, is a lifethreatening neuropsychiatric disorder characterized by mounting fever, extreme hyperactivity and stuporous exhaustion. While lethal catatonia is more commonly recognized as an outgrowth of a functional psychiatric disorders, it may also develop in association with a medical disorders directly or indirectly affecting the CNS. While the pathogenesis of lethal catatonia is unclear, disordered functioning within the diencephalon and other brain areas possibly involving alterations in central dopaminergic transmission. Neuroleptic malignant syndrome may be considered a neuroleptic-induced iatrogenic form of lethal catatonia. In lethal catatonia of functional orgin, neuroleptics appear inadequate in treatment and may aggravate or complicate episodes of the disorder. Although some authors argue that steroids are useful, ECT appears to be the preferred treatment in functional origin. In organic origin, treatment should be directed at the underlying disorder and ECT may help relieve symptoms. Familiarity with the clinical features and varied etiologies is essential for prognosis and effective management. The authors presented three cases showing lethal catatonia syndrome’s clinical feature with a brief review.

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Lethal catatonia syndrome