만성정신분열병의 우울증상에 대한 Nortriptyline의 효과

• 영문명: The Effect of Nortriptyline on Depressive Symptoms in Chronic Schizophrenia： A double blind clinical study
• 발행기관: 대한신경정신의학회
• 저자명: 崔龍成 金容植 趙斗英
• 간행물 정보: 『신경정신의학』제24권 제3호, 363~369쪽, 전체 7쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1985.08.31

영문 초록

Authors studied the antidepressant effect of nortriptyline on depression and withdrawal in admitted male chronic achizophrenic patients by dcuble blind methcd for 5 weeks of duration at Yong-In Mental Hospital. Sample size was forty one cases consisting of 21 nortriptyline grcup and 20 placebogroup. The results were as follows： 1) In nortriptyline group, there were no significant change in m ean BPRS scores, compared with those of placeto group. However decrease of mean BPRS score frcm 11.50 to 6.54 was observed. 2) There were no significant change in mean BDI scores in nortriptyline group compared with those of placebo group but also decrease of mean BDI score from 40. 90 to 35.23 was observed. 3) In nortriptyline group there were no significant change of total DOTES scores throughout the study. None of total DOTES scores was found to be significantly d ifferen t from those of placebo group.

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