학술논문
Skin-directed radiotherapy for primary cutaneous T-cell lymphomas
이용수 0
- 영문명
- 발행기관
- 대한방사선종양학회
- 저자명
- Ha Un Kim Yeon Joo Kim Mi Woo Lee Woo Jin Lee Sang-wook Lee Youngju Song Byungchul Cho Si Yeol Song
- 간행물 정보
- 『대한방사선종양학회지』제42권 제3호, 228~236쪽, 전체 9쪽
- 주제분류
- 의약학 > 종양학
- 파일형태
- 발행일자
- 2024.09.30
4,000원
구매일시로부터 72시간 이내에 다운로드 가능합니다.
이 학술논문 정보는 (주)교보문고와 각 발행기관 사이에 저작물 이용 계약이 체결된 것으로, 교보문고를 통해 제공되고 있습니다.
국문 초록
Purpose: To evaluate the efficacy and toxicities of skin-directed radiotherapy (RT) in primary cutaneous T-cell lymphoma (CTCL).
Materials and Methods: We retrospectively analyzed 57 CTCL lesions treated with skin-directed RT between January 2000 and December 2022. Lesions were categorized into three distinct groups: early-stage disease treated with local RT, advanced-stage disease treated with local RT, and advanced-stage disease treated with total skin electron beam therapy (TSEBT). Treatment outcomes, including response rates, recurrence patterns, and local progression probability, were assessed for each group.
Results: Mycosis fungoides (MF) constituted 90.9% of the advanced-stage pathologies, while CD4+ primary cutaneous small/medium T-cell lymphoproliferative disorder was common in the early stage lesions (55%). Median RT doses were 30.6 Gy, 27 Gy, and 32 Gy for the local RT with early stage, the local RT with advanced stage, and TSEBT with advanced stage, respectively. The complete response rates were high across the groups: 95.5%, 70.8%, and 90.9%, respectively. Seven local recurrences (29.2%) occurred in the local RT group with advanced stage, while seven patients (63.6%) in the TSEBT group experienced local failure. All recurrences were observed in lesions and patients with MF. Acute toxicities were mainly grade 1 or 2, with no grade 3 or higher events. No significant association between RT dose and local progression rates in MF lesions was found.
Conclusion: Skin-directed RT in CTCL is effective for local control and well-tolerated with less toxicity
영문 초록
목차
Introduction
Materials and Methods
Results
Discussion and Conclusion
Statement of Ethics
Conflict of Interest
Funding
Author Contributions
Data Availability Statement
Supplementary Materials
References
해당간행물 수록 논문
- 대한방사선종양학회지 제42권 제3호 목차
- Could neoadjuvant radiation dose escalation increase tumor response and recurrence-free survival in patients with locally advanced rectal cancer?
- Advancing radiation therapy through smartwatch technology to monitor anxiety
- Supervised deep learning-based synthetic computed tomography from kilovoltage cone-beam computed tomography images for adaptive radiation therapy in head and neck cancer
- Evidence-based clinical recommendations for hypofractionated radiotherapy: exploring efficacy and safety - Part 3. Genitourinary and gynecological cancers
- Recurrence pattern of glioblastoma treated with intensity-modulated radiation therapy versus three-dimensional conformal radiation therapy
- Unilateral radiotherapy for tonsillar cancer with multiple ipsilateral neck lymph nodes
- Optimizing target and diaphragmatic configuration, and dosimetric benefits using continuous positive airway pressure in stereotactic ablative radiotherapy for lung tumors
- Oncological outcomes in patients with residual triple-negative breast cancer after preoperative chemotherapy
- Long-term treatment of metastatic adenoid cystic carcinoma with sequential brachytherapy and stereotactic body radiotherapy
- Skin-directed radiotherapy for primary cutaneous T-cell lymphomas
참고문헌
관련논문
의약학 > 종양학분야 BEST
- 식도암에서 근치적 절제술 후 방사선치료의 역할
- Impact of adaptive radiotherapy on survival in locally advanced nasopharyngeal carcinoma treated with concurrent chemoradiotherapy
- 노인 두경부암 환자의 생존에 있어 노쇠의 의의
의약학 > 종양학분야 NEW
- 대한두경부종양학회지 제40권 제2호 목차
- 볼지방덩이의 일측성 지방종: 증례 보고
- 소아 이하선 악성 종양의 국내 발생 추이 및 이하선 수술에 대한 단일 기관에서의 경험에 대한 후향적 분석 연구
최근 이용한 논문
교보eBook 첫 방문을 환영 합니다!
신규가입 혜택 지급이 완료 되었습니다.
바로 사용 가능한 교보e캐시 1,000원 (유효기간 7일)
지금 바로 교보eBook의 다양한 콘텐츠를 이용해 보세요!