학술논문
Evidence-based clinical recommendations for hypofractionated radiotherapy: exploring efficacy and safety - Part 3. Genitourinary and gynecological cancers
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- 영문명
- 발행기관
- 대한방사선종양학회
- 저자명
- Gyu Sang Yoo Soo-Yoon Sung Jin Ho Song Byoung Hyuck Kim Yoo-Kang Kwak Kyung Su Kim Hwa Kyung Byun Yeon-Sil Kim Yeon Joo Kim
- 간행물 정보
- 『대한방사선종양학회지』제42권 제3호, 171~180쪽, 전체 10쪽
- 주제분류
- 의약학 > 종양학
- 파일형태
- 발행일자
- 2024.09.30
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국문 초록
Hypofractionated radiotherapy (RT) has become a trend in the modern era, as advances in RT techniques, including intensity-modulated RT and image-guided RT, enable the precise and safe delivery of high-dose radiation. Hypofractionated RT offers convenience and can reduce the financial burden on patients by decreasing the number of fractions. Furthermore, hypofractionated RT is potentially more beneficial for tumors with a low α/β ratio compared with conventional fractionation RT. Therefore, hypofractionated RT has been investigated for various primary cancers and has gained status as a standard treatment recommended in the guidelines. In genitourinary (GU) cancer, especially prostate cancer, the efficacy, and safety of various hypofractionated dose schemes have been evaluated in numerous prospective clinical studies, establishing the standard hypofractionated RT regimen. Hypofractionated RT has also been explored for gynecological (GY) cancer, yielding relevant evidence in recent years. In this review, we aimed to summarize the representative evidence and current trends in clinical studies on hypofractionated RT for GU and GY cancers addressing several key questions. In addition, the objective is to offer suggestions for the available dose regimens for hypofractionated RT by reviewing protocols from previous clinical studies.
영문 초록
목차
Introduction
KQ 1. What is the Applicable Hypofractionated RT Regimen in Prostate Cancer?
KQ 2. What is the Applicable Hypofractionated RT Regimen in Bladder Cancer?
KQ 3. What are the Indications, Efficacy, and Toxicity of SBRT Boost in Cervical Cancer Patients instead of Brachytherapy Boost?
KQ 4. What are the Indications, Efficacy, and Toxicity of Hypofractionated Postoperative Radiotherapy in Gynecological Cancer Patients?
Conclusion
Statement of Ethics
Conflict of Interest
Funding
Author Contributions
Data Availability Statement
References
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