노인에서의 만성 C형간염 치료

• 영문명: Treatment of Chronic Hepatitis C in Older Adults
• 발행기관: 대한임상노인의학회
• 저자명: 연종은(Jong Eun Yeon)
• 간행물 정보: 『대한임상노인의학회지』제24권 제3호, 93~99쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2023.12.31

영문 초록

Worldwide, more than 100 million people were infected with chronic hepatitis C (CHC). Prevalence in Korea was estimated at as much as 0.6%. Because of the progressive aging of hepatitis C virus-infected people, the number of cases of CHC in older adults has been increasing. In older patients with CHC, greater acceleration of fibrosis with aging and higher risk of hepatocellular carcinoma development have been reported. Currently, with the popular all-oral combination of direct-acting antiviral (DAA) treatment of CHC, the rates of sustained virologic response and treatment-related adverse events between patients younger and older than 65 years are not significantly different. Although clinicians should consider drug-drug interactions, comorbid medical condition, risk of disease progression, and long-term benefits of viral eradication by DAA, older age should not be a barrier to treatment.

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키워드

Aged Hepatitis C chronic Direct acting antiviral