국내 개, 고양이, 사람 및 환경에서 유래된 항생제 내성 그람음성세균

• 영문명: The Antimicrobial Resistant Gram-negative Bacteria Originated from Canines, Felines, Environments, and Humans in South Korea
• 발행기관: 한국동물보건학회
• 저자명: 홍준성 배일권
• 간행물 정보: 『한국동물보건학회지』2권 3호, 113~127쪽, 전체 15쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2023.09.30

영문 초록

The report of distribution and antimicrobial resistance rates in clinical hospitals in South Korea has been well-documented. However, the description of prevalence and antimicrobial resistance rate in veterinary hospitals is relatively rare. The aims of this study were to describe the prevalence and antimicrobial resistance rate for gram-negative bacteria originated from canines, felines, environments, and humans in South Korea. We collected bacteria from the rectal swabs of companion animals (dogs and cats), stool samples of humans (pet owners and medical staffs), and swabs of veterinary hospital surfaced in 16 veterinary hospitals. The isolates for antimicrobial susceptibility were performed by the agar disk diffusion method. Third- and fourth-generation extended-spectrum cephalosporin (ESC) resistance genes were identified by PCR and sequencing. A total of 740 Escherichia coli , 133 Klebsiella pneumoniae, 132 Acinetobacter baumannii , and 100 Pseudomonas aeruginosa isolates were recovered on MacConkey agar from companion animals, humans, and veterinary hospital environment samples for 2019 - 2020. The ESC resistant rates showed 36.3%, 40.6%, 18.2%, and 0% in E. coli , K. pneumoniae , A. baumannii , and P. aeruginosa, respectively. The most of the ESC resistance genes were blaCMY-2, blaDHA-1, and blaCTX-M-type. Our results indicate that the antimicrobial resistance rate including ESC was similar to that in the clinical field except carbapenem. In addition, the genus, species, and an timicrobial resistance determinants of gram-negative bacteria collected from samples were similar between the clinical and veterinary fields.

목차

1. Introduction

2. Materials and methods

3. Results

4. Discussion

5. Conclusion

CONFLICT OF INTEREST

ACKNOWLEDGEMENT

ORCID

REFERENCES

키워드

Companion animal Canine Feline Antimicrobial resistance Gram-negative bacteria Veterinary hospital