Objectives “Uihwi” is a book of Korean medicine written under the pseudonym of Geumlisanin in the late Joseon Dynasty. At that time, it was published by collecting famous prescriptions of experience across the country, and it can be said to be an important data in that it gives a glimpse of oriental medicine at the end of the Joseon Dynasty, but there are not many studies on “Uihwi”. This paper attempted to examine the characteristics of oriental medicine at the end of the Joseon Dynasty. Methods Using the text of “Uihwi” as the subject of research, comparing to other medical texts, and to examine the position of acupuncture in it. Results Thus, the following conclusions were obtained. “Uihwi” was mainly edited by citing medical books published in Joseon, and is also a comprehensive medical book that combines the experiences of himself and other medical professionals. In addition, it can be seen that medicine at that time was very practical by presenting uncomplicated prescriptions. In the case of acupuncture, an acupuncture method that synthesizes the clinical achievements of Joseon was presented. Conclusions The practicality was emphasized by reducing the theoretical explanation, and based on this practicality, efforts were made to aggregate medicine in the late Joseon Dynasty.