Distal vaginal atresia: a report of a rare type found a late-term fetus and its histological comparison with the normal pelvis

• 영문명: Distal vaginal atresia: a report of a rare type found a late-term fetus and its histological comparison with the normal pelvis
• 발행기관: 대한해부학회
• 저자명: Ji Hyun Kim Zhe-Wu Jin Hiroshi Abe Gen Murakami José Francisco Rodríguez-Vázquez Nobuyuki Hinata
• 간행물 정보: 『Anatomy and Cell Biology』Vol.55(4), 475~482쪽, 전체 8쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2022.12.31

영문 초록

Solitary distal vaginal atresia is generally caused by a transverse septum or an imperforate hymen. We found a novel type of distal vaginal atresia in a late-term fetus (gestational age approximately 28 weeks) in our histology collection. This fetus had a vaginal vestibule that was closed and covered by a thick subcutaneous tissue beneath the perineal skin in the immediately inferior or superficial side of the imperforate hymen. The uterus, uterine tube, anus, and anal canal had normal development. The urethral rhabdosphincters were well-developed and had a normal topographical relationship with the vagina, but the urethrovaginal sphincter was absent. Thus, vaginal descent seemed to occur normally and form the vestibule. However, the external orifice of the urethra consisted of a highly folded duct with hypertrophied squamous epithelium. Notably, the corpus cavernosum and crus of the clitoris had poor development and were embedded in the subcutaneous tissue, distant from the vestibule. Normally, the cloacal membrane shifts from the bottom of the urogenital sinus to the inferior aspect of the thick and elongated genital tubercle after establishment of the urorectal septum. Therefore, we speculate there was a failure in the transposition of the cloacal membrane caused by decreased elongation of the genital tubercle. The histology of this anomaly strongly suggested that the hymen does not represent a part of the cloacal membrane, but is instead a product that appears during the late recanalization of the distal vagina after vaginal descent. The transverse septum was also likely to form during this recanalization.

목차

Introduction

Materials and Methods

Results

Discussion

ORCID

Author contributions

Conflicts of Interest

References

키워드

Imperforate hymen Genital tubercle Cloacal membrane Corpus cavernosum of the clitoris Anomaly