학술논문
The relationship between metabolic syndrome and its components with bladder cancer: a systematic review and meta-analysis of cohort studies
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- 영문명
- The relationship between metabolic syndrome and its components with bladder cancer: a systematic review and meta-analysis of cohort studies
- 발행기관
- 한국역학회
- 저자명
- Mozhgan Ahmadinezhad Maedeh Arshadi Elahe Hesari Maedeh Sharafoddin Hosein Azizi Farzad Khodamoradi
- 간행물 정보
- 『Epidemiology and Health』44, 1~11쪽, 전체 11쪽
- 주제분류
- 의약학 > 면역학
- 파일형태
- 발행일자
- 2022.01.01
4,120원
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국문 초록
영문 초록
A previous meta-analysis, entitled “The association between metabolic syndrome and bladder cancer susceptibility and prognosis: an updated comprehensive evidence synthesis of 95 observational studies involving 97,795,299 subjects,” focused on all observational studies, whereas in the present meta-analysis, we focused on cohort studies to obtain more accurate and stronger evidence to evaluate the association between metabolic syndrome and its components with bladder cancer. PubMed, Embase, Scopus, and Web of Science were searched to identify studies on the association between metabolic syndrome and its components with bladder cancer from January 1, 2000 through May 23, 2021. The pooled relative risk (RR) and 95% confidence intervals (CI) were used to measure this relationship using a random-effects meta-analytic model. Quality appraisal was undertaken using the Newcastle-Ottawa Scale. In total, 56 studies were included. A statistically significant relationship was found between metabolic syndrome and bladder cancer 1.09 (95% CI, 1.02 to 1.17), and there was evidence of moderate heterogeneity among these studies. Our findings also indicated statistically significant relationships between diabetes (RR, 1.23; 95% CI, 1.16 to 1.31) and hypertension (RR, 1.07; 95% CI, 1.01 to 1.13) with bladder cancer, but obesity and overweight did not present a statistically significant relationship with bladder cancer. We found no evidence of publication bias. Our analysis demonstrated statistically significant relationships between metabolic syndrome and the risk of bladder cancer. Furthermore, diabetes and hypertension were associated with the risk of bladder cancer.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
CONCLUSION
SUPPLEMENTARY MATERIALS
CONFLICT OF INTEREST
FUNDING
ACKNOWLEDGEMENTS
AUTHOR CONTRIBUTIONS
ORCID
REFERENCES
키워드
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