로타바이러스 감염된 Vero 세포에서 Lactobacillus ruminus와 Bifidobacterium longum의 케모카인 변화 분석

• 영문명: Chemokine Effects of Lactobacillus ruminus, and Bifidobacterium longum in Rotavirus Infected Vero Cells
• 발행기관: 한국유산균프로바이오틱스학회
• 저자명: 최예진(Yae Jin Choi) 신혜순(Hea Soon Shin)
• 간행물 정보: 『Current Topics in Lactic Acid Bacteria and Probiotics』Current Topics in Lactic Acid Bacteria and Probiotics 5권 2호, 47~51쪽, 전체 5쪽
• 주제분류: 농수해양 > 식품과학
• 파일형태: PDF
• 발행일자: 2019.12.30

영문 초록

Probiotics, such as Lactobacillus spp. and Bifidobacterium spp. are reported to have the multiple potential health benefits including blocking gastroenteric pathogens, reduce gut permeability, enhancing immune response and anti-viral effects. In this study, we explored whether LR211 and BL205, 206 exert on MCP-1 and IL-8 chemokines responses in rotavirus infected vero cells. And we investigated anti-rotaviral activity of Lactobacillus spp. and Bifidobacterium spp. isolated against rotavirus by plaque assay. As a results, all of them were not toxic to vero cells. Three probiotics, BL205, 206 and LR211, increased release of MCP-1 and IL-8 in Wa rotavirus infected vero cells compared to control. This anti-viral effects of LR211 and BL205, 206 can be explained that they modulate immune response by inducing MCP-1 and IL-8 chemokines.

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재료 및 방법

결과 및 고찰

감사의 글

키워드

anti-Rotaviral activity Bifidobacterium species Lactobacillus species