Stress relief and weight gain effects of needle-free injection for foot-and-mouth disease vaccine in pigs

• 발행기관: 한국예방수의학회
• 저자명: 채원석(Won-Seok Chae) 박은기(Eun-Kee Park) 박광일(Kwang-Il Park) 김석(Suk Kim) 이후장(Hu-Jang Lee)
• 간행물 정보: 『Journal of Preventive Veterinary Medicine』Vol.45, No.4, 183~187쪽, 전체 5쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2021.12.31

영문 초록

This study compared the immune responses, stress relief and weight gains of needle or needle-free intramuscular and needle-free intradermal vaccination in pigs. When the same amount of a foot-and-mouth disease (FMD) vaccine was administered to pigs, antibody titers at 4 weeks after the 1st and 2nd FMD vaccination were not significantly different between the needle (IM-S) and needle-free (NM-P250) intramuscularly vaccinated groups, but the weight gain of NM-P250 was significantly increased compared to that of IM-S at 8 weeks after the 2nd FMD vaccination (p<0.05). In addition, serum cortisol concentrations of NM-P250 were considerably decreased compared to those of IM-S on the 5th and 7th day after the 1st and 2nd FMD vaccination (p<0.05). However, the antibody titers of IM-S vaccinated with 2 mL of FMD vaccine were significantly increased compared to those of the needle-free intradermal vaccinated group with 0.5 mL of FMD vaccine at 4 weeks after the 1st and 2nd FMD vaccination (p<0.05). In conclusion, the needle-free intramuscular injection for the FMD vaccination can be chosen for weight gain and stress relief in pigs.

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Needle-free injection FMD vaccination weight gain stress relief pigs