Utilization of lyophilized platelet-rich plasma in esthetic facial treatment

• 발행기관: 대한미용의학회
• 저자명: Teh-Yang Cheng
• 간행물 정보: 『Journal of Cosmetic Medicine』Vol.4, No.2, 101~107쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2020.12.30

영문 초록

Platelet-rich plasma (PRP) has a variety of functions. Activated platelets release various growth factors and are involved in the tissue repair process. Growth factors from platelets induce fibroblast activation, which produces a new extracellular matrix and collagen. The PRP treatment has been widely used in many surgical and medical fields. However, uncertainties in the quality of the PRP preparation may cause unpredictability in the treatment results. The standardized separation method with quantization of lyophilized platelet-rich plasma (L-PRP) might enhance treatment accuracy. After processing in central laboratory, L-PRP is packed in vials in powder form and readily used immediately after reconstitution. We utilized clinical photography, Visia, DermaLab USB, and histology examination to compare the results before and after treatments. Besides improvements in clinical photos and Visia scores, ultrasound images showed obvious increasing in collagen densities in dermal and subcutaneous layers. The histology study suggested increased collagen formation but without signs of fibrotic change or foreign body reaction. The elastin stain suggested an increased elastic fiber density. The improvement noted by the instruments and histology findings correlated with the improvement of skin texture, decreased wrinkles, and positive clinical outcomes. These results highlight L-PRP’s potential as an efficient and convenient process compared to the original PRP in skin rejuvenation treatment.

목차

Introduction

Case report

Discussion

Conflicts of interest

References

키워드

lyophilized platelet-rich plasma neo-collagenesis platelet-rich plasma skin rejuvenation