양측 눈꺼풀 결막에 국한되어 발생한 면역글로불린 G4 관련 안질환

• 영문명: Isolated Bilateral Tarsal Conjunctival Immunoglobulin G4-related Ophthalmic Disease
• 발행기관: 대한검안학회
• 저자명: 국경윤(Kyung Yun Kook) 문현식(Hyun Sik Moon) 윤현정(Hyeon Jeong Yoon) 최 원(Won Choi)윤경철(Kyung Chul Yoon)
• 간행물 정보: 『Annals of optometry and contact lens』Vol.19 No.1, 22~25쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2020.03.30

영문 초록

Purpose: To report a case of isolated bilateral tarsal conjunctival immunoglobulin G4 (IgG4)-related ophthalmic disease. Case summary: A 34-year-old male presented with both upper tarsal mass refractory with medical treatment at local hospital from 4 months ago. Slit-lamp examination showed elevated multi-lobular masses on both upper tarsal conjunctiva. Immunochemical stain on specimen showed the ratio of the IgG4+ to IgG+ cells was approximately over 80% and the mean number of IgG4-positive plasma cells was over 100 per high-power field. Therefore, we could finally diagnose his illness as IgG4-related ophthalmic disease. There was no evidence of systemic involvement in other examinations such as blood tests or radiologic examination performed in the rheumatology department of internal medicine. Conclusions: IgG4-related ophthalmic disease is well known to occur in the orbit, especially in the lacrimal gland. However, there are no reported cases of tarsal conjunctival IgG4-related ophthalmic disease in Korea. Therefore, if a tumor is found in the tarsal conjunctiva, appropriate pathologic examination should be performed with the possibility of IgG4-related ophthalmic disease.

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키워드

Conjunctival neoplasms IgG4-related ophthalmic disease Immunoglobulin G4-related disease Tarsal conjunctiva