노인에서 항콜린성 약물의 사용

• 영문명: The Use of Anticholinergic Drugs in the Elderly
• 발행기관: 대한노인정신의학회
• 저자명: 김혜림(Hyerim Kim) 김병수(Byung-Soo Kim) 장성만(Sung Man Chang)
• 간행물 정보: 『노인정신의학』노인정신의학 제24권 제2호, 51~59쪽, 전체 9쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2020.10.30

영문 초록

Anticholinergic drugs are commonly prescribed for treatment in specific clinical conditions in the elderly. Despite these therapeutic benefits, the use of anticholinergic drugs is limited due to central or peripheral anticholinergic side effects. Especially in the elderly, since long-term use of anticholinergic drugs is related to mild cognitive impairment and dementia, it is necessary to prescribe anticholinergic drugs appropriately. In this review, we try to cover pathophysiology, prevalence of anticholinergic drugs, measuring tools of anticholinergic activity. Also, the negative effects on cognitive function, psychiatric symptoms, delirium, hospitalization, functionality and mortality, and the benefits and limitations of discontinuing anticholinergic drugs are discussed. Finally, we suggest appropriate prescriptions of anticholinergic drugs for the elderly in various clinical conditions.

목차

서 론

항콜린성 약물의 병태생리

항콜린성 약물의 사용 현황

항콜린성 활성의 측정

항콜린성 약물의 영향

항콜린성 약물 중단의 이익과 제한점

결론 및 제언

REFERENCES

키워드

Anticholinergic Aged Cognitive dysfunction Dementia