HO약침의 약동학 연구

• 영문명: A Pharmacokinetic Study of HO-pharmacopuncture Solution
• 발행기관: 임상약침학회
• 저자명: 정철(Chul Jung) 김학주(Hak-Ju Kim) 황지혜(Ji Hye Hwang)
• 간행물 정보: 『임상약침학회학회지』대한면역약침학회지 제6권 제1호, 21~28쪽, 전체 8쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2017.12.30

영문 초록

Objectives : A pharmacokinetic study of HO-pharmacopuncture solution was performed to rats. Blood, urine and stool samples were collected and analyzed in gas chromatogram (GC). Methods : Rats were injected intraperitoneally with HO (Carthami fructus)-pharmacopuncture solution (0.5 ml) and blood samples were collected from tail artery and urine and stool samples were acquired in individual metabolic cages. Results : GC chromatogram analysis of HO-pharmacopuncture solution showed a total of 12 peaks. In serum samples, the largest number of peak was identified on day 1 and six peaks were observed at the same retention time as standard HO until 10 days. In stool and urine samples, peaks at 45 min were observed at the same retention time as standard HO until 10 days. Conclusions : These results may be interpreted as most of components of HO was not accumulated in the serum but excreted as urine and stool.

목차

Ⅰ. 서 론

Ⅱ. 재료 및 방법

Ⅲ. 결 과

Ⅳ. 고 찰

Ⅴ. 결 론

참고문헌

키워드

HO pharmacopuncture Carthami fructus gas chromatography (GC) pharmacokinetic