CS 약침의 항염증 및 항산화 활성에 대한 연구

• 영문명: Anti-oxidant and anti-inflammatory effects of CS Yakchim
• 발행기관: 임상약침학회
• 저자명: 김학주(Hak-Ju Kim) 김수경(Soo-Kyung Kim) 최일환(Il-Hwan Choi) 정철(Chul Jung) 여서원(Hsu-Yuan Lu) 두경희(Kyeong-Hee Doo) 김민경(Min-Kyung Kim) 조승연(Seung-Yeon Cho) 박정미(Jung-Mi Park) 고창남(Chang-Nam Ko) 박성욱(Seong-Uk Park)
• 간행물 정보: 『임상약침학회학회지』대한면역약침학회지 제1권 제1호, 43~51쪽, 전체 9쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2012.12.30

영문 초록

Objectives : CS has been used as effective pain reducing pharmacoacupunture in clinical fields, however its constituents and physiological activity have not been yet certified by experiment. This experimental research was to analyze the component of CS Yakchim and prove its anti-oxidant and anti-inflammatory effect. Methods : Content of protein, glucose, crude fat and crude ash was calculated. Anti-oxidant effect was measured using 1,1-diphenyl-2-picryl hydrazyl(DPPH) free radical scavenging activity. Anti-inflammatory effect was measured with COX-2 kit and RAW 264.7 macrophage. the concentration of TNF-α and IL-6 was measured by Enzyme-linked immuno-sorbent assay. Results : CS Yakchim is consist of 0.17% of protein, 0.32% of glucose, 95.19% of crude fat and 0.32% of crude ash. CS showed better anti-oxidant effect than its control sample. CS COX-2 inhibiting capacity was better than its Indomethacin control sample. Inflammatory cytokine production was reduced but not at transcription level. Conclusions : These results showed that CS Yakchim is consist protein, glucose, crude fat and crude ash. CS Yakchim anti-oxidant and anti-inflammatory effect.

목차

Ⅰ. 서 론

Ⅱ. 재료 및 방법

Ⅲ. 연구결과

Ⅳ. 고 찰

Ⅴ. 결 론

참고문헌

키워드

Anti-oxidant effect Anti-inflammatory effect CS Yakchim Taxus cuspidata Pharmacopuncture Nam Sang Cheon Immuno Yakchim