학술논문
The Comparison of Mydriatic Effect Between Two Drugs of Different Mechanism
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- 영문명
- 발행기관
- 대한안과학회
- 저자명
- Ji-Hyun Park Young-Chun Lee Se-Youp Lee
- 간행물 정보
- 『The Korean Journal of Ophthalmology』Vol.23 No.1, 40~42쪽, 전체 3쪽
- 주제분류
- 의약학 > 기타의약학
- 파일형태
- 발행일자
- 2009.03.30
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국문 초록
영문 초록
Purpose: To maximize effective use of mydriatic drugs through comparing the pupillary dilation effects between
1% tropicamide and 2.5% phenylephrine.
Methods: Fifty people requiring pupillary dilation were divided into 3 groups. Group 1 was treated with one drop of
1% tropicamide in the right eye and one drop of 2.5% phenylephrine in the left eye. Group 2 was treated twice
during a 5-minute interval with 1% tropicamide in the right eye. Group 3 was treated twice during a 5-minute
interval with 2.5% phenylephrine in the right eye. Groups 2 and 3 were treated with 2.5% phenylephrine and 1%
tropicamide in the left eye, administered during a 5-minute interval. The pupillary size was measured in all groups
for 40 minutes following eye drops administration.
Results: The mean patient age was 15.7 years. Group 1 included 10 patients, and groups 2 and 3 included 20
patients each. Eight patients in group 1 and 16 patients in group 2 developed a larger right pupil. Fourteen patients
in group 3 developed a larger left pupil.
Conclusions: Our study showed that 1% tropicamide, with its parasympathetic antagonistic mechanism of action,
was more effective at inducing pupillary dilation than 2.5% phenylephrine, and the combination of 1% tropicamide
and 2.5% phenylephrine was more effective than multiple drops of single eye drops.
목차
Materials and Methods
Results
Discussion
References
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