난치 각막상피질환 환자에서 5% 혈청알부민 점안액의 효과: 임상증례 및 문헌고찰

• 영문명: The Effect of 5% Serum Albumin on Intractable Corneal Epithelial Keratitis: a Case Series and Literature Review
• 발행기관: 대한안과학회
• 저자명: 황유숙(Yousook Hwang) 조양경(Yang Kyung Cho)
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume59,number5, 1~7쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2018.04.30

영문 초록

Purpose: We report five cases of intractable epithelial keratitis in which 5% serum albumin showed significant effects as a topical treatment when compared with other previous conservative treatments based on a literature review. Methods: This was a retrospective observational case series of five patients with intractable corneal epithelial keratitis who used serum albumin as a topical treatment. All patients had already been using other conservative treatments such as non-preserved artificial tears and autologous serum eye drops. The size of the epithelial defect and the time taken for closure of the epithelial defect were observed. Results: The study involved five patients with intractable corneal epithelial disease with a mean follow-up time of 6 months. The epithelial lesions improved with the use of 5% serum albumin from the beginning of treatment and lasted throughout the follow-up period. The mean time to complete epithelial closure using 5% serum albumin eye drops was 21 days. Conclusions: Treatment with 5% serum albumin eye drops may have a significant and stable effect in the treatment of intractable corneal epithelial disease. J Korean Ophthalmol Soc 2018;59(5):403-409

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대상과 방법

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키워드

Intractable corneal epithelial keratitis Serum albumin eye drop